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Studies Spotlight Diet, Supplements for Knee Pain

By Serena Gordon

HealthDay Reporter

TUESDAY, May 23, 2017 (HealthDay News) — Fiber helps lower cholesterol, stabilize blood sugar levels and hold the bowels running easily, however a brand new research suggests it may additionally scale back knee pain from arthritis.

Researchers discovered that individuals who ate probably the most fiber reported lowered osteoarthritis knee ache by as much as 60 %. However, X-rays didn’t present any distinction of their knees in comparison with those that consumed much less fiber.

A second research seemed on the results of the dietary supplement chondroitin on knee ache. That research — sponsored by a maker of the supplements — discovered that taking chondroitin every day was linked to much less knee ache and improved perform.

But at the least two bone specialists famous that the potent sort of chondroitin used within the research in all probability is not obtainable within the United States, and the security of long-term every day use of the complement is unknown.

Both research have been revealed on-line May 23 within the Annals of the Rheumatic Diseases.

“With each of those research, the hazard is that individuals are considering they’re making a change of their arthritis, however they could solely be masking the pain. Neither research has confirmed a change within the pure historical past of osteoarthritis,” defined Dr. Victor Khabie, who was not concerned with the research. He is co-director of the Orthopedic and Spine Institute at Northern Westchester Hospital, in Mount Kisco, N.Y.

Fiber is present in fruits, greens, nuts and whole grains. It helps to make individuals really feel full and scale back calorie consumption. Fiber can also be believed to scale back inflammation, the researchers stated.

The fiber research checked out knowledge from two different research. One included almost 5,000 individuals who had or have been liable to osteoarthritis. Their health has been monitored since a minimum of 2006, when their common age was 61.

The second set of knowledge got here from the Framingham Offspring research, and included simply over 1,200 individuals. That research started in 1971, and consists of knowledge from 1993 to 1994, when the typical age of members was 54. They have been adopted till 2002-2005.


In the primary group, median fiber consumption ranged from 21 grams a day to 9 grams a day. In the Framingham group, the very best group ate a median of 26 grams every day. The lowest group had almost 14 grams day by day.

People who ate probably the most fiber have been at decrease danger of creating osteoarthritis knee ache, the research discovered. For these within the first group who ate probably the most fiber, the danger went down by 30 %. For these within the Framingham group who ate probably the most fiber, the danger was 61 % lower than those that ate the least fiber.

The researchers additionally discovered that individuals who ate extra fiber have been much less more likely to have worsening knee ache.

Lead researcher Zhaoli Dai, a postdoctoral researcher at Boston University, stated, “There is a robust hyperlink amongst obesity, inflammation and painful knee osteoarthritis. We speculate that eating more fiber will increase satiety and subsequently reduces complete caloric intake and reduces body weight.”

But Dai added that as a result of the research is an observational one, it will probably’t show a cause-and-effect relationship.

Dr. Matthew Hepinstall is affiliate director of the Lenox Hill Hospital Center for Joint Preservation & Reconstruction in New York City.

He agreed that the research can’t show a causal relationship.

“Nevertheless, when mixed with lately revealed knowledge suggesting decrease charges of osteoarthritis development in sufferers who lose weight — additionally solely an affiliation — an image is rising that wholesome life might have measurable results on the danger of progressive osteoarthritis ache,” Hepinstall stated.

But he famous that loads of individuals who keep wholesome and lively life additionally develop painful osteoarthritis. So, Hepinstall added that “a high-fiber diet should not be seen as a proven strategy for preventing arthritis.”

Dai stated: “As the average intake of fiber is about 15 grams per day among Americans. This amount is way below the recommended nutritional goal according to the Dietary Guidelines for Americans 2015-2020, which recommends 22.4 grams/day for women and 28 grams/day for men aged 51 years and above.”

According to the Dietary Guidelines for Americans 2015-2020, a traditional serving of high-fiber cereal incorporates 9 or extra grams of fiber. A cup of navy beans supplies almost 10 grams, and an apple has about 5 grams of fiber.


The second research checked out chondroitin sulfate. It’s a chemical discovered naturally within the cartilage of the knee, in response to the U.S. National Library of Medicine.

The research included greater than 600 individuals from 5 European nations who had been recognized with knee osteoarthritis. The sufferers have been randomly assigned to one in every of three remedy teams.

One group was given 800 milligrams (mg) of “pharmaceutical grade” chondroitin every day and one placebo capsule to imitate 200 mg of the ache reliever celecoxib (Celebrex). Another group was given a 200-mg celecoxib capsule and a placebo to imitate the chondroitin capsule. The third group was given two placebo drugs.

The research lasted six months. Doctors assessed the research individuals at one, three and 6 months.

Reductions in ache and enhancements in joint perform have been higher in individuals handled with chondroitin or celecoxib at three and 6 months. The researchers stated that chondroitin offered comparable aid to celecoxib.

Khabie stated, “It looks like there’s an anti-inflammatory or pain-relieving effect when chondroitin is taken in a very purified, very well-controlled state, but that’s probably not what’s available off-the-shelf [in the United States].” He famous that chondroitin is a complement, and within the United States dietary supplements aren’t regulated in the identical means that medicine are.

Khabie additionally stated that the security of taking chondroitin long-term is not recognized.

Hepinstall echoed Khabie’s considerations concerning the chondroitin research, but in addition stated chondroitin is perhaps “notably well-suited for sufferers who can’t take NSAID medications.” NSAIDs, or non-steroidal anti-inflammatory medicine, embrace ibuprofen (Motrin, Advil), naproxen (Aleve) and aspirin.

WebMD News from HealthDay


SOURCES: Zhaoli Dai, Ph.D., postdoctoral researcher, Boston University; Victor Khabie, M.D., chief, division of surgical procedure, chief, sports activities drugs, and co-director of the Orthopedic and Spine Institute, Northern Westchester Hospital, Mount Kisco, N.Y.; Matthew S. Hepinstall, M.D., affiliate director, Lenox Hill Hospital Center for Joint Preservation and Reconstruction, New York City; May 23, 2017, Annals of the Rheumatic Diseases, on-line

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