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Pregnancy Not Risk Factor for Breast Cancer Return

By Robert Preidt


HealthDay Reporter

       
       

SATURDAY, June three, 2017 (HealthDay News) — There’s excellent news for youthful breast most cancers survivors: Pregnancy doesn’t appear to extend the probabilities that their illness will return, researchers report.

       

“Our findings confirm that pregnancy after breast cancer should not be discouraged, even for women with ER-positive [estrogen-sensitive] cancer,” stated research writer Dr. Matteo Lambertini, a medical oncologist on the Institut Jules Bordet, in Brussels.

       

Lambertini’s group tracked outcomes for greater than 1,200 breast most cancers survivors. The analysis confirmed that those that turned pregnant didn’t have any larger danger of most cancers recurrence and demise over a mean of 10 years follow-up, in comparison with women who didn’t develop into pregnant.

       

This was true even when the women had skilled estrogen receptor (ER)-positive tumors.

       

ER-positive breast most cancers is fueled by estrogen, and it was thought that elevated ranges of the hormone throughout being pregnant might set off most cancers cells which will linger within the physique after remedy to develop.

       

But the findings might assist dispel long-held fears that being pregnant might improve the prospect of breast most cancers’s return, even for women with ER-positive cancers, the researchers stated.

       

However, they identified that women with ER-positive most cancers have to interrupt any post-surgery (adjuvant) hormone remedy if they’re making an attempt to get pregnant.  This hormone remedy helps forestall most cancers recurrence, and it is strongly recommended that women obtain it for at the least 5 years and in some instances as much as 10 years.

       

“When deciding how long to wait before becoming pregnant, patients and doctors should consider each woman’s personal risk for recurrence, particularly for women who need adjuvant hormone therapy,” Lambertini added.

       

Dr. Bruce Johnson is ASCO’s President-Elect and chief medical analysis officer at Dana-Farber Cancer Institute in Boston. Reviewing the brand new findings, he careworn that “breast cancer typically is somewhat unusual in women of childbearing age, but it does happen.”

       

The research “saw no increased risk with pregnancy in the ER-positive population,” Johnson stated. “If anything, the risk was a little bit lower, which is a little bit counterintuitive. It certainly appears that pregnancy will not add risk for the cancer returning.”

       

The researchers have been to current the findings Saturday in Chicago on the annual assembly of the American Society of Clinical Oncology (ASCO). Because these findings have been introduced at a medical assembly, they need to be thought-about preliminary till revealed in a peer-reviewed journal.

     

WebMD News from HealthDay

Sources

SOURCES: Bruce Johnson, M.D., ASCO President-Elect, chief medical analysis officer, Dana-Farber Cancer Institute, and professor, Harvard Medical School, Boston; American Society of Clinical Oncology, information launch, June three, 2017

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